Abstract
A new synthetic route to afford 2-amino-5-aryl thiazoles has been developed. The starting
aminothiazole derivative can be arylated at position 5 with aryl iodides under palladium-catalyzed
conditions. Mechanistic studies suggest a proton-abstraction pathway for this transformation.
Key words
palladium - catalysis - cross-coupling - heterocycles - Heck reaction
References and Notes
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